Selank Protocol
Tuftsin analog studied for anxiolytic and immune-modulating effects, mainly in Russian research literature.
- Cycle
- 4–8 weeks
Evidence Level: Investigational / Theoretical
Primarily preclinical or very limited human data — mechanism-based reasoning more than a demonstrated clinical effect. Treat as investigational.
Human evidence: Human trials exist primarily within Russian research literature; independent replication outside that literature is limited.
Animal evidence: Rodent anxiolytic-behavior and immune-marker studies.
Introduction & Mechanism of Action
Tuftsin analog studied for anxiolytic and immune-modulating effects, mainly in Russian research literature.
Synthetic analog of the immunomodulatory peptide tuftsin; studied for GABAergic and BDNF-related effects associated with anxiolytic (anxiety-reducing) action without the sedation typical of benzodiazepines.
Receptors/targets: No confirmed classical receptor — proposed GABAergic and neurotrophin-pathway modulation
Areas of Research Interest
- Anxiolytic research
- Immune-modulation studies
Benefits Reported in Research
- Anxiolytic research
- Immune-modulation studies
Reported Research Dosing Range
The figures below are cited from published research literature and protocol references — they describe what has been studied, not a personal prescription or instruction.
Reported range: 250–500 mcg
Reported frequency: 1× daily, intranasal
Reported cycle duration: 4–8 weeks
Escalation & maintenance: A dedicated weekly escalation and maintenance schedule specific to this peptide has not yet been published here — follow the dose range and frequency above, titrating conservatively from the low end, and consult a physician before adjusting.
Side Effects
- Nasal irritation (intranasal route)
Contraindications
- Pregnancy
Drug interactions
- Theoretical interaction with other CNS-active/anxiolytic medications not well characterized
Safety
- No meaningful human safety database outside Russian research literature
- Independent international replication is limited
Independent replication outside the original research literature is limited; not FDA/EMA approved.
Expected Results & Comparison
Selank targets anxiolytic/stress research rather than sleep-onset directly — for sleep-regulation research specifically, DSIP is the more directly relevant peptide in this catalog, though its evidence base is also sparse.